The new and innovative way to treat facial aging and skin laxity.



Endor Technologies Hyalgen Serum increases the effects of radio frequency (RF) facial skin tightening treatments, clinically proven to make them 18 times more effective. The Hyalgen Serum works with RF treatments to improve skin firmness, smoothness and brightness thus reducing fine lines, wrinkles and skin imperfections revealing younger, healthier-looking skin.


  • Improving the results of RF treatments by 18 times
  • Natural lifting of the skin
  • Reduction to fine lines, wrinkles and skin imperfections
  • Improvement to skin complexion
  • Visible results after the first treatment
  • An increased skin firmness and improved skin structure

A significant improvement in the quality of the skin through an increased production of hyaluronic acid, collagen and elastin from the Hyalgen Serum.

Hyalgen Serum can also be used to boost and accelerate skin healing, improving the recovery time and effects of the following treatments:

  • Chemical Peels
  • Laser Resurfacing Treatments
  • Plasma Pen
  • Microneedling
  • Injectables - e.g. BOTOX & Fillers
Product Specification

Adverse effects: No adverse effects have been described.

Precautions: For external use only. Do not apply on broken or irritated skin. Avoid contact with eyes and mucous membranes. Not for use in pregnant or nursing women. Do not apply more Hyalgen Serum than recommended. Follow each RF energy device manufacturer"s recommendations for treatment. Hyalgen Serum is a product studied and designed only for RF treatments.

Biodistribution and elimination: studies with biopsies and spectrophotometry detection demonstrate that nanoparticles do not pass through the epidermis and they are completely eliminated from the body through natural defoliation in 24 hours.

Volume: 20 vials / 3 ml per vial


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The Results - Before & After

Hyalgen Serum and radiofrequency combination boosts and accelerates the reduction of fine lines, wrinkles and skin imperfections in the face and neck area. Tightening, firming and brightening to reveal younger, and healthier looking skin with results visible after the first treatment.

In a double-blind placebo controlled clinical study, there was a significant difference in using an adjuvant serum with the CD44 Enhancer in, which is the active ingredient in the Hyalgen Serum, with RF vs RF alone (90% vs 55%). Measures were taken one week after completing six treatment sessions.

Before and after images show the visible improvement to skin tightness, wrinkles, complexion and overall health of the skin.

All our products pass through rigorous efficacy studies in a hospital environment and under medical supervision. Impartial instrumental measures demonstrate that the products are effective and their results are extremely visible. None of our products are animal tested.


The pictures have not been retouched or modified in any way.
Clinical study performed at the Instituto de Fotomedicina del Centro Médico Teknon under the supervision of Doctor Joan Ramón Garcés, Doctor Eva Ciscar and the researcher Gabriel Buendí­a.

How To Use The Serum

  1. Each 3 ml vial covers the entire face area or neck area for one session. Prior to each RF session, apply Hyalgen Serum on dry and clean skin with a soft massage until completely absorbed.
  2. Once the Hyalgen Serum has been absorbed perform the RF treatment per standard protocol. Consult us to know the RF protocol which was performed in the clinical study.